You are here: Home > CANNABINOIDS > Cannabinoids in cancer pain

Cannabinoids 2010;5(1):1-3 (January 23, 2010)

Article of the Month

Cannabinoids in cancer pain

Franjo Grotenhermen

nova-Institut, Chemiepark Knapsack, Industriestraße, D-50354 Hürth, Germany,

This article of the month presents results of a clinical study conducted in the UK and Romania, which evaluated the efficacy of a THC:CBD cannabis extract (Sativex®) and a THC cannabis ex-tract in the treatment of 177 patients with cancer pain, who experienced inadequate pain reduction despite intake of opioids [Johnson et al. J Pain Symptom Manage, 2010, in press]. Sativex resulted in a significant improvement of mean pain scores on a primary outcome measure, a Numerical Rating Scale (NRS) from 0 to 10 compared to placebo (improvement of -1.37 versus -0.69), while the THC extract caused a non-significant improvement (-1.01). Conversely, there was a significant improvement in total pain according to the Brief Pain Inventory-Short Form in the THC-group compared to placebo but a non-significant improvement following Sativex.

cannabis, THC, cannabidiol, chronic pain, cancer, clinical trial.

PDF of the full text ]

IACM Conference 2019

The IACM Conference 2019 will be held on October 31 - November 2, 2019, at Estrel Hotel, Berlin, Germany. More information coming soon! Please see here information on past conferences.

Supported conferences

STCM Conference, 19 January 2019, University Hospital Bern, Switzerland

Cann10, 14-16 October 2018, Tel Aviv Israel.

Members only

Please click here to visit the Members Only Area with a film to honour Prof Raphael Mechoulam, 
Please click here to become a member.

IACM on Twitter

Follow us on twitter @IACM_Bulletin where you can send us inquiries and receive updates on research studies and news articles.